p-Cresyl sulfate potassium

CAS No. 91978-69-7

p-Cresyl sulfate potassium( Potassium p-tolyl sulfate | p-Tolyl sulfate potassium salt | p-Cresol sulfate potassium )

Catalog No. M27100 CAS No. 91978-69-7

p-Methylphenyl potassium sulfate is a prototype protein-bound uremic toxin derived from the metabolites of tyrosine and phenylalanine through liver.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    p-Cresyl sulfate potassium
  • Note
    Research use only, not for human use.
  • Brief Description
    p-Methylphenyl potassium sulfate is a prototype protein-bound uremic toxin derived from the metabolites of tyrosine and phenylalanine through liver.
  • Description
    p-Methylphenyl potassium sulfate is a prototype protein-bound uremic toxin derived from the metabolites of tyrosine and phenylalanine through liver.
  • In Vitro
    Cell Viability Assay Cell Line:Primary osteoblastic cells Concentration:0.05, 0.125, 0.25, 0.5 mM Incubation Time:24 h Result:Decreased cell viability in a dose-dependent manner.Cell Proliferation Assay Cell Line:Primary osteoblastic cells Concentration:0.05, 0.125, 0.25, 0.5 mM Incubation Time:24 h Result:Increased DNA fragmentation and decreased cell proliferation.Western Blot Analysis Cell Line:Primary osteoblastic cells Concentration: 0.125 mM Incubation Time:24 h Result:Induced rapid and sustained phosphorylation of JNK.
  • In Vivo
    Animal Model:CKD mice modrlDosage:10 mg/kg Administration:i.p.Result:Increased fasting plasma glucose concentration and plasma cholesterol levels.
  • Synonyms
    Potassium p-tolyl sulfate | p-Tolyl sulfate potassium salt | p-Cresol sulfate potassium
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    cholinesterase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    91978-69-7
  • Formula Weight
    226.29
  • Molecular Formula
    C7H7KO4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (552.39 mM)
  • SMILES
    [K+].Cc1ccc(OS([O-])(=O)=O)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Barman S, Das AC. Residual effect of pre-emergence herbicides on microbial activities in relation to mineralization of C, N and P in the Gangetic alluvial soil of West Bengal, India. Environ Monit Assess. 2015 Jul;187(7):465.
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